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Neoprene gloves are a type of thick, waterproof rubber gloves. Neoprene is a trademark name for polychloroprene, which has been registered by DuPont. This product is a family of synthetic rubber that has a wide number of consumer and industrial applications, ranging from wet suits and scuba gloves to fan belts and laptop sleeves.

The chemical properties of neoprene make it very popular for situations where a item requires the ability to add a layer of insulation type material while providing a snug fit. Neoprene gloves are often used in combat, fire prevention and related situations. One of the benefits of neoprene gloves is the cost. These types of gloves have all the benefit of more expensive, breathable fabrics at a much lower price point. If the situation requires neoprene gloves to be insulated against extreme cold or underwater situations, the air spaces within the gloves are filled with nitrogen.

Neoprene was first developed by chemists at DuPont in 1930. The work was inspired by a lecture given by Fr. Julius Nieuwland at the University of Notre Dame. He developed a jelly with similar properties to rubber when exposed to sulfur dichloride. DuPont purchased the patent rights to this product and worked together with Nieuwland to develop this further.